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    Folic Acid

    Folic Acid in Tradeasia

    IUPAC Name

    -

    Cas Number

    59-30-3

    HS Code

    -

    Formula

     

     

    Basic Info

    Appearance

    White or Slight Yellow Crystal Powder

    Common Names

    Vitamin B9

    Packaging

    25 Kg Bag

    Brief Overview

    Folic acid is a tasteless, odourless, yellow-orange crystalline powder that is insoluble in alcohol, ether and other organic solvents. It is the synthetic form of Vitamin and provides folates which are essential for DNA synthesis, repair and methylation.

    Specifications

     Property Units Value
    Appearance -  Yellow crystalline powder
    Water content % 8.5
    Residue on ignition % 0.30
    Chromatographic % 2.0
    Assay % 97.0~102.0
    Total plate count cfu/g 1000
    Coliforms MPN/100g 30
    Mold & yeast cfu/g 100
    Salmonella - Negative

     

    Dosage for Poultry

    • Newly Hatched Chicks: 1-1.5 mg/kg feed 
    • Young and Growing: 1-1.5 mg/kg feed 
    • Laying Hens: 1-1.5 mg/kg feed 
    • Breeders: 2-3 mg/kg feed 
    • Broiler Chicks: 1.5-2 mg/kg feed 
    • Broiler Adults: 2-4 mg/kg feed

    Manufacturing Process

    The present invention is directed to a novel process for the production of folic acid in high yield and utilizing a novel diimine as an intermediate. This diimine is formed by reacting 2-substituted malondialdehyde with p-aminobenzoyl-L-glutamic acid. This diimine may be converted into folic acid by reacting the diimine with triaminopyrimidinone in the presence of sulphite.

     

    • Higher stability and bioavailability as compared with natural folates. 
    • Essential for the transfer and interconversion of single-carbon units, which includes formyl, methyl and methylene groups. 
    • Essential to cell division and protein synthesis, in particular nucleotide biosynthesis and remethylation of homocysteine. 
    • Necessary for normal immune function. 
    • Deficiency leads to impaired cell division and alterations of protein synthesis, which results in macrocytic anaemia and leukopenia (reduced number of white blood cells). 
    • Deficiency leads to poor growth and feathering, anaemic appearance and perosis in chicks and turkeys.

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